Figure 6

Fig. 6. Structural differentiation of actin network in lamellipodium. Electron microscopy of Xenopus keratocytes (a-c) or Xenopus fibroblasts (d-f) after regular extraction in the presence of PEG and phalloidin (a, d) or after unprotected extraction without PEG and phalloidin (b, c, e and f). Boxed areas from (b) and (e) are enlarged in (c) and (f) respectively. Actin network at lamellipodial rear disassembled in the course of unprotected extraction, whereas front zone remained as dense as in control cells. Bar, 1 µm.