Figure 1

Fig. 1. Multiple branching of actin filaments in lamellipodia. Electron microscopy of lamellipodia of Xenopus keratocytes (a-g) and fibroblasts (h-o) showing overviews of the leading edge (a, h) and enlargements of the boxed regions (b-g, i-o). Many examples of filaments with tightly spaced multiple branches (cyan) can be visualized in lamellipodia despite the high overall density of the actin network. Bar, 0.5 µm.